脊柱手术中不同麻醉药物剂量对术后认知功能的影响研究
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陈雷
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锦州市第二医院，辽宁锦州，121000
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摘要：脊柱手术是常见的外科治疗方式，麻醉环节的管理，特别是麻醉药的挑选和用量把控，会直接影响患者术后的恢复状态。术后认知功能障碍是脊柱术后常出现的并发症，它的出现和麻醉药对中枢神经系统的抑制作用有关，但当前还没有针对不同麻醉药、不同用量如何影响脊柱手术患者术后认知的系统性剂量 - 效应关联研究，让临床优化麻醉方案缺少精准的参考依据。本文重点针对脊柱手术中常用的丙泊酚、瑞芬太尼、右美托咪定等麻醉药，在不同用量下对患者术后认知功能的影响展开系统探讨。
关健词：麻醉药物剂量；术后认知功能；脊柱手术 |
Study on the Effects of Different Anesthetic Drug Doses on Postoperative Cognitive Function in Spinal Surgery
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Lei Chen
Jinzhou Second Hospital, Jinzhou, Liaoning, 121000 , China
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Abstract：Spinal surgery is a common surgical treatment method. The management of anesthesia, especially the selection and dosage control of anesthetics, directly affects patients' postoperative recovery status. Postoperative cognitive dysfunction is a common complication after spinal surgery, which is related to the inhibitory effect of anesthetics on the central nervous system. However, there is currently no systematic dose-response correlation study on how different anesthetics and dosages affect postoperative cognitive function in spinal surgery patients, leaving a lack of precise reference for clinical optimization of anesthesia protocols. This article focuses on systematically exploring the effects of commonly used anesthetics such as propofol, remifentanil, and dexmedetomidine on postoperative cognitive function in spinal surgery patients at different dosages.
Keywords : anesthetic drug dosage；postoperative cognitive function；spinal surgery
参考文献
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